Posts classified under: Faculty

Weizhe Hong, Ph.D.

Weizhe Hong, Ph.D.

Research

Dr. Weizhe Hong is an Associate Professor in the Department of Biological Chemistry and the Department of Neurobiology at UCLA David Geffen School of Medicine. Dr. Hong received a B.S. degree in biological sciences at Tsinghua University. When he was in high school and college, he worked with Zengyi Chang, on mechanisms of protein folding and microbial stress response, first at Tsinghua University and then at Peking University. He received his PhD degree in 2012 at Stanford University, under the guidance of Liqun Luo. His PhD research focused on the cellular and molecular mechanisms of wiring specificity during olfactory system development. He was a Helen Hay Whitney Fellow in David Anderson’s Laboratory, working on neural mechanisms underlying social and emotional behaviors. Dr. Hong received the Genetics Society of America’s Larry Sandler Memorial Award for the best PhD dissertation on the Drosophila research, and presented the Larry Katz Memorial Lecture in the Cold Spring Harbor Conference for the best PhD dissertation on neural circuit research.

Publications

Hong W, Kennedy A, Burgos-Artizzu X, Zelikowsky M, Navonne S, Perona P, Anderson DJ. (2015) Automated measurement of mouse social behaviors using depth sensing, video tracking, and machine learning. Proc. Natl. Acad. Sci. USA. 112, E5351-5360.

Pearce MM, Spartz EJ, Hong W, Luo L, Kopito RR. (2015) Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain. Nature Communications. 13, 6:6768.

Ward A*, Hong W*, Favaloro V, Luo L. (2015) Toll Receptors Instruct Axon and Dendrite Targeting and Participate in Synaptic Partner Matching in a Drosophila Olfactory Circuit. Neuron. 85, 1013-1028. (*co-first authors)

Hong W, Kim DW, Anderson DJ. (2014) Antagonistic Control of Social versus Repetitive Self-Grooming Behaviors by Separable Amygdala Neuronal Subsets. Cell. 158, 1348-1361.

Hong W, Luo L. (2014) Genetic Control of Wiring Specificity in the Fly Olfactory System. Genetics. 196, 17-29.

Hong W. (2013) Assembly of A Neural Circuit. Science. 342, 1186. (doi: 10.1126/science.1247568)

Mosca TJ*, Hong W*, Dani VS, Favaloro V, Luo L. (2012) Trans-synaptic Teneurin signaling in neuromuscular synapse organization and target choice. Nature. 484, 237-241. (*co-first authors)

Hong W, Mosca TJ, Luo L. (2012) Teneurins instruct synaptic partner matching in an olfactory map. Nature. 484, 201-207.

Hong W*, Wu YE*, Fu X, Chang Z. (2012) Chaperone-dependent mechanisms for acid resistance in enteric bacteria. Trends in Microbiology. 20, 328-335. (*co-first authors)

de Wit J*, Hong W*, Luo L, Ghosh A. (2011) Role of leucine-rich repeat proteins in the development and function of neural circuits. Annual Review of Cell and Developmental Biology. 27, 697-729. (*co-first authors)

Hong W, Zhu H, Potter CJ, Barsh G, Kuruzu M, Zinn K, Luo L. (2009) Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map. Nature Neuroscience. 12, 2542-2550.

Hong W and Luo L. (2009) Dendritic tiling through TOR signaling. EMBO Journal. 28, 3783-3784.

Wu YE*, Hong W*, Zhang L, Liu C, Chang Z. (2008) Conserved amphiphilic feature is essential for periplasmic chaperone HdeA to support acid resistance in enteric bacteria. Biochemical Journal. 412, 389-397. (*co-first authors)

Jiao W, Hong W, Li P, Sun S, Ma J, Qian M, Hu M, Chang Z. (2008) The dramatically increased chaperone activity of small heat shock protein IbpB is retained for an extended period of time after the stress condition is removed. Biochemical Journal. 410, 63-70.

Liu C, Mao K, Zhang M, Sun Z, Hong W, Li C, Peng B, Chang Z. (2008) The SH3-like domain switches its interaction partners to modulate the repression activity of mycobacterial Iron-dependent transcription regulator in response to metal Ion fluctuations. Journal of Biological Chemistry. 283, 2439-2453.

Hong W, Jiao W, Hu J, Zhang J, Liu C, Fu X, Shen D, Xia B, Chang Z. (2005) Periplasmic protein HdeA exhibits chaperone-like activity exclusively within stomach pH range by transforming into disordered conformation. Journal of Biological Chemistry. 280, 27029-27034.

Liu Y, Fu X, Shen J, Zhang H, Hong W, Chang Z. (2004) Periplasmic proteins of Escherichia coli are highly resistant to aggregation: reappraisal for roles of molecular chaperones in periplasm. Biochemical and Biophysical Research Communications. 316, 795-801.

David Glanzman, Ph.D.

David Glanzman, Ph.D.

Research

Dr. Glanzman is interested in the cell biology of learning and memory in simple organisms. In our research we use two animals, the marine snail Aplysia californica, and the zebrafish (Danio rerio). Work on Aplysia: This invertebrate has a comparatively simple nervous system (~ 20,000 neurons) that provides a valuable experimental model for understanding the cellular mechanisms that underlie simple forms of learning, such as habituation, sensitization, and classical conditioning. Another experimental advantage of Aplysia is that sensory and motor neurons that mediate specific reflexes of the animal can be placed into dissociated cell culture where they will reform their synaptic connections. These in vitro sensorimotor synapses are extremely useful for cellular and molecular studies of short- and long-term learning-related synaptic plasticity. Currently, my laboratory is investigating the mechanisms that underlie the persistence of memory: how are memories maintained in our brains over long periods of time? Two phenomena related to memory persistence that have attracted significant interest in recent years are memory reconsolidation and memory erasure. Regarding memory reconsolidation, it has been found that when a long-term memory is reactivated through a reminder stimulus the memory becomes temporarily labile; during this period the memory can be permanently lost by various treatments, such as protein synthesis inhibition, until it reconsolidates and is once more stable. Memories can also be lost, apparently permanently, if a specific kinase, known as PKM, is inhibited. This suggests that the activity of PKM is critical for the maintenance of long-term memories. We are currently performing studies on Aplysia to try to unravel the mechanisms that underlie memory reconsolidation and memory erasure. These studies should provide insights into how memories persist. They may also facilitate treatments for such disorders of long-term memory as posttraumatic stress disorder (PTSD). Work on the zebrafish: The zebrafish has significant advantages for genetic and molecular studies of behavior, including studies of learning and memory. The zebrafish is amenable to both forwards and reverse genetics. Furthermore, although it is a vertebrate with a complex vertebrate nervous system, it possesses reflexive behaviors that are mediated by relatively simple neural circuits in the spinal cord and brainstem. Finally, zebrafish larvae are transparent, which facilitates the use of imaging techniques to study learning-related neural activity within the intact animal. We are interested in the neural basis of nonassociative and associative behavioral modification of the startle reflex.

Publications

Roberts Adam C, Bill Brent R, Glanzman David L Learning and memory in zebrafish larvae Frontiers in neural circuits, 2013; 7: 126.

Glanzman David L PKM and the maintenance of memory F1000 biology reports, 2013; 5: 4.

Glanzman David L David L. Glanzman Current biology : CB, 2012; 22(21): R895-7. Cai Diancai, Pearce Kaycey, Chen Shanping, Glanzman David L Reconsolidation of long-term memory in Aplysia Current biology : CB, 2012; 22(19): 1783-8.

Glanzman David L Behavioral neuroscience: no easy path from genes to cognition Current biology : CB, 2012; 22(9): R302-4.

Glanzman David L Olfactory habituation: fresh insights from flies Proceedings of the National Academy of Sciences of the United States of America, 2011; 108(36): 14711-2.

Cai Diancai, Pearce Kaycey, Chen Shanping, Glanzman David L Protein kinase M maintains long-term sensitization and long-term facilitation in aplysia The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(17): 6421-31.

Roberts Adam C, Reichl Jun, Song Monica Y, Dearinger Amanda D, Moridzadeh Naseem, Lu Elaine D, Pearce Kaycey, Esdin Joseph, Glanzman David L Habituation of the C-start response in larval zebrafish exhibits several distinct phases and sensitivity to NMDA receptor blockade PloS one, 2011; 6(12): e29132.

Issa Fadi A, O’Brien Georgeann, Kettunen Petronella, Sagasti Alvaro, Glanzman David L, Papazian Diane M Neural circuit activity in freely behaving zebrafish (Danio rerio) The Journal of experimental biology, 2011; 214(Pt 6): 1028-38.

Glanzman David L Common mechanisms of synaptic plasticity in vertebrates and invertebrates Current biology : CB, 2010; 20(1): R31-6.

Glanzman David L Ion pumps get more glamorous Nature neuroscience, 2010; 13(1): 4-5.

Esdin Joseph, Pearce Kaycey, Glanzman David L Long-term habituation of the gill-withdrawal reflex in aplysia requires gene transcription, calcineurin and L-type voltage-gated calcium channels Frontiers in behavioral neuroscience, 2010; 4(1): 181.

Glanzman David L Habituation in Aplysia: the Cheshire cat of neurobiology Neurobiology of learning and memory, 2009; 92(2): 147-54.

Villareal Greg, Li Quan, Cai Diancai, Fink Ann E, Lim Travis, Bougie Joanna K, Sossin Wayne S, Glanzman David L Role of protein kinase C in the induction and maintenance of serotonin-dependent enhancement of the glutamate response in isolated siphon motor neurons of Aplysia californica The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(16): 5100-7.

Bedi Supinder S, Cai Diancai, Glanzman David L Effects of axotomy on cultured sensory neurons of aplysia: long-term injury-induced changes in excitability and morphology are mediated by different signaling pathways Journal of neurophysiology, 2008; 100(6): 3209-24.

Fulton Daniel, Condro Michael C, Pearce Kaycey, Glanzman David L The potential role of postsynaptic phospholipase C activity in synaptic facilitation and behavioral sensitization in Aplysia Journal of neurophysiology, 2008; 100(1): 108-16.

Glanzman DL New tricks for an old slug: The critical role of postsynaptic mechanisms in learning and memory in Aplysia, Prog. Brain Res, 2008; 169C: 277-292.

Glanzman David L New tricks for an old slug: the critical role of postsynaptic mechanisms in learning and memory in Aplysia Progress in brain research, 2008; 169(12): 277-92.

Glanzman David L Octopus conditioning: a multi-armed approach to the LTP–learning question Current biology : CB, 2008; 18(12): R527-30.

Cai Diancai, Chen Shanping, Glanzman David L Postsynaptic regulation of long-term facilitation in Aplysia Current biology : CB, 2008; 18(12): 920-5.

Villareal Greg, Li Quan, Cai Diancai, Glanzman David L The role of rapid, local, postsynaptic protein synthesis in learning-related synaptic facilitation in aplysia Current biology : CB, 2007; 17(23): 2073-80.

Jami SA, Wright WG, Glanzman DL. Differential classical conditioning of the gill-withdrawal reflex in Aplysia recruits both NMDA receptor-dependent enhancement and NMDA receptor-dependent depression of the reflex, J Neurosci, 2007; 27(12): 3064-8. Download

Glanzman, D. L Simple minds: the neurobiology of invertebrate learning and memory, Invertebrate Neurobiology, 2007; 347-380.

Villareal G, Li Q, Cai D, Glanzman DL The role of rapid, local, postsynaptic protein synthesis in learning-related synaptic facilitation in Aplysia, Curr. Biol, 2007; 17(23): 2073-2080. Download

Jami Shekib A, Wright William G, Glanzman David L Differential classical conditioning of the gill-withdrawal reflex in Aplysia recruits both NMDA receptor-dependent enhancement and NMDA receptor-dependent depression of the reflex The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007; 27(12): 3064-8.

Glanzman DL. The cellular mechanisms of learning in Aplysia: of blind men and elephants, Biol Bull, 2006; 210(3): 271-9. Download

Glanzman David L The cellular mechanisms of learning in Aplysia: of blind men and elephants The Biological bulletin, 2006; 210(3): 271-9. Li Q,

Roberts AC, Glanzman DL. Synaptic facilitation and behavioral dishabituation in Aplysia: dependence on release of Ca2+ from postsynaptic intracellular stores, postsynaptic exocytosis, and modulation of postsynaptic AMPA receptor efficacy, J Neurosci, 2005; 25(23): 5623-37. Download

Li Quan, Roberts Adam C, Glanzman David L Synaptic facilitation and behavioral dishabituation in Aplysia: dependence on release of Ca2+ from postsynaptic intracellular stores, postsynaptic exocytosis, and modulation of postsynaptic AMPA receptor efficacy The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005; 25(23): 5623-37.

Roberts AC, Glanzman DL. Learning in Aplysia: looking at synaptic plasticity from both sides, Trends Neurosci, 2003; 26(12): 662-70. Download Ezzeddine Y, Glanzman DL. Prolonged habituation of the gill-withdrawal reflex in Aplysia depends on protein synthesis, protein phosphatase activity, and postsynaptic glutamate receptors, J Neurosci, 2003; 23(29): 9585-94. Download

Chitwood RA, Li Q, Glanzman DL. Serotonin facilitates AMPA-type reponses in isolated siphon motor neurons of Aplysia in culture, J Physiol, 2001; 534(Pt 2): 501-10. Download

Murphy GG, Glanzman DL. Cellular analog of differential classical conditioning in Aplysia: disruption by the NMDA receptor antagonist DL-2-amino-5-phosphonovalerate, J Neurosci, 1999; 19(23): 10595-602. Download

Mark Frye, Ph.D.

Biography

Dr. Frye began his research career at Union College, then received his PhD at the University of Washington. As a postdoctoral fellow at Berkeley and then at Caltech, he began to work on multi-sensory processing and motor control of flight in fruit flies. He is currently a member of the Department of Physiological Science, and teaches courses in integrative and comparative animal physiology. He is the reciepient of a Sloan Foundation Fellowship, and his laboratory examines sensory fuison and sensory-motor integration for the control of walking and flight in fruit flies.

Publications

Duistermars BJ Frye MA A magnetic tether system to investigate visual and olfactory mediated flight control in Drosophila JoVE, 2008; 23: .

Theobald, JC Frye, MA Animal Behavior: flying back-to-front, Curr. Biol. , 2008; 18(4): r169. Chow DM Frye MA Context dependent olfactory enhanced optomotor flight control in Drosophila, J. Exp. Biol. , 2008; 211: 2478-2485.

Duistermars, BJ Frye, MA Cross-modal visual input for odor tracking during fly flight, Curr. Biol. , 2008; 18(4): 270-275.

Theobald JC Duistermars BJ Ringach DL Frye MA Flies see second order motion, Curr. Biol. , 2008; 18(11): r464. Duistermars, B.J. Reiser, M.B. Zhu, Y. Frye, M.A. Dynamic properties of large-field and small-field optomotor flight responses in Drosophila, Journal of Comparative Physiology A, 2007; in press: .

Reynolds, A. Frye, M.A. Free-flight odor tracking in Drosophila is consistent with a mathematically optimal intermittent scale-free search, PLoS ONE, 2007; 2(4): 354.

Frye, MA The neuromechanics of fly flight control, Invertebrate Neurobiology, 2007; 209-229.

Duistermars, BJ Chow, D Condro, M Frye, MA The spatial, temporal, and contrast properties of expansion and rotation flight optomotor responses in Drosophila, J. Exp. Biol. , 2007; 210: 3218-3227. Frye, MA Dickinson, MH Visual edge orientation shapes free-flight behavior in Drosophila, Fly, 2007; 3: 153-154.

Humbert, J.S. Frye, M.A. Extracting behaviorally relevant retinal image motion cues via wide-field integration, Proc. IEEE American Controls Conference, 2006; 2724-2729.

Frye, MA Dickinson, MH Closing the loop between neurobiology and flight behavior in Drosophila Current opinion in neurobiology. , 2004; 14(6): 729-36.

Frye, MA Dickinson, MH Fly flight: a model for the neural control of complex behavior Neuron. , 2001; 32(3): 385-8.

S. Thomas Carmichael, M.D., Ph.D.

S. Thomas Carmichael, M.D., Ph.D.

Research

S. Thomas (Tom) Carmichael is a neurologist and neuroscientist at the Geffen School of Medicine at UCLA. Dr. Carmichael is a Professor and Vice Chair for Research and Progams in the Department of Neurology, with active laboratory and clinical interests in stroke and neurorehabilitation, and how the brain repairs from injury. He received his M.D. and Ph.D. degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident in 1997-1998. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001, studying mechanisms of axonal sprouting, with a clinical emphasis on neurorehabilitation and stroke. He has been on the UCLA faculty since 2001. Dr. Carmichael’ s laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the Neurorehabilitation and Stroke clinical services at UCLA.

Publications

Li Songlin, Nie Esther H, Yin Yuqin, Benowitz Larry I, Tung Spencer, Vinters Harry V, Bahjat F Rena, Stenzel-Poore Mary P, Kawaguchi Riki, Coppola Giovanni, Carmichael S Thomas GDF10 is a signal for axonal sprouting and functional recovery after stroke Nature neuroscience, 2015; .

Rosenzweig Shira, Carmichael S Thomas The axon-glia unit in white matter stroke: Mechanisms of damage and recovery Brain research, 2015; 1623: 123-134.

Prakash Roshini, Carmichael S Thomas Blood-brain barrier breakdown and neovascularization processes after stroke and traumatic brain injury Current opinion in neurology, 2015; .

Dobkin Bruce H, Carmichael S Thomas The Specific Requirements of Neural Repair Trials for Stroke Neurorehabilitation and neural repair, 2015; 1623: .

Zhu Suwei, Nih Lina, Carmichael S Thomas, Lu Yunfeng, Segura Tatiana Enzyme-Responsive Delivery of Multiple Proteins with Spatiotemporal Control Advanced materials (Deerfield Beach, Fla.), 2015; 27(24): 3620-5.

Omura Takao, Omura Kumiko, Tedeschi Andrea, Riva Priscilla, Painter Michio W, Rojas Leticia, Martin Joshua, Lisi Véronique, Huebner Eric A, Latremoliere Alban, Yin Yuqin, Barrett Lee B, Singh Bhagat, Lee Stella, Crisman Tom, Gao Fuying, Li Songlin, Kapur Kush, Geschwind Daniel H, Kosik Kenneth S, Coppola Giovanni, He Zhigang, Carmichael S Thomas, Benowitz Larry I, Costigan Michael, Woolf Clifford J Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS Neuron, 2015; 86(5): 1215-27.

Kathirvelu Balachandar, Carmichael S Thomas Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery Metabolic brain disease, 2015; 30(2): 449-59.

Lam Jonathan, Carmichael S Thomas, Lowry William E, Segura Tatiana Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture Advanced healthcare materials, 2015; 4(4): 534-9.

Hinman Jason D, Lee Monica D, Tung Spencer, Vinters Harry V, Carmichael S Thomas Molecular disorganization of axons adjacent to human lacunar infarcts Brain : a journal of neurology, 2015; 138(Pt 3): 736-45.

Lugassy Claire, Zadran Sohila, Bentolila Laurent A, Wadehra Madhuri, Prakash Roshini, Carmichael S Thomas, Kleinman Hynda K, Péault Bruno, Larue Lionel, Barnhill Raymond L Angiotropism, pericytic mimicry and extravascular migratory metastasis in melanoma: an alternative to intravascular cancer dissemination Cancer microenvironment : official journal of the International Cancer Microenvironment Society, 2014; 7(3): 139-52.

Lam Jonathan, Lowry William E, Carmichael S Thomas, Segura Tatiana Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells Advanced functional materials, 2014; 24(44): 7053-7062.

Barratt Harriet E, Lanman Tyler A, Carmichael S Thomas Mouse intracerebral hemorrhage models produce different degrees of initial and delayed damage, axonal sprouting, and recovery Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014; 34(9): 1463-71.

López-Valdés Héctor E, Clarkson Andrew N, Ao Yan, Charles Andrew C, Carmichael Stanley Thomas, Sofroniew Michael V, Brennan Kevin C Memantine enhances recovery from stroke Stroke; a journal of cerebral circulation, 2014; 45(7): 2093-100.

Gleichman Amy J, Carmichael S Thomas Astrocytic therapies for neuronal repair in stroke Neuroscience letters, 2014; 565(7): 47-52.

Overman Justine J, Carmichael S Thomas Plasticity in the injured brain: more than molecules matter The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2014; 20(1): 15-28.

Carmichael S Thomas Reflections: neurology and the humanities. Molecular medicine and the art of brain repair Neurology, 2013; 81(24): 2143-4.

Rosenzweig Shira, Carmichael S Thomas Age-dependent exacerbation of white matter stroke outcomes: a role for oxidative damage and inflammatory mediators Stroke; a journal of cerebral circulation, 2013; 44(9): 2579-86.

Moshayedi Pouria, Carmichael S Thomas Hyaluronan, neural stem cells and tissue reconstruction after acute ischemic stroke Biomatter, 2013; 3(1): .

Carmichael S Thomas, Krakauer John W The promise of neuro-recovery after stroke: introduction Stroke; a journal of cerebral circulation, 2013; 44(6 Suppl 1): S103.

Hinman Jason D, Rasband Matthew N, Carmichael S Thomas Remodeling of the axon initial segment after focal cortical and white matter stroke Stroke; a journal of cerebral circulation, 2013; 44(1): 182-9.

Brumm Andrew J, Carmichael S Thomas Not just a rush of blood to the head Nature medicine, 2012; 18(11): 1609-10.

Krakauer John W, Carmichael S Thomas, Corbett Dale, Wittenberg George F Getting neurorehabilitation right: what can be learned from animal models? Neurorehabilitation and neural repair, 2012; 26(8): 923-31.

Carmichael S Thomas Opinion & special articles: a guide from fellowship to faculty: Nietzsche and the academic neurologist Neurology, 2012; 79(14): e116-9.

Overman Justine J, Clarkson Andrew N, Wanner Ina B, Overman William T, Eckstein Ilya, Maguire Jaime L, Dinov Ivo D, Toga Arthur W, Carmichael S Thomas A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke Proceedings of the National Academy of Sciences of the United States of America, 2012; 109(33): E2230-9.

Chesselet Marie-Francoise, Carmichael S Thomas Animal models of neurological disorders Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012; 9(2): 241-4.

Sozmen Elif G, Hinman Jason D, Carmichael S Thomas Models that matter: white matter stroke models Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012; 9(2): 349-58.

Zhang Jianjun, Tokatlian Talar, Zhong Jin, Ng Quinn K T, Patterson Michaela, Lowry William E, Carmichael S Thomas, Segura Tatiana Physically associated synthetic hydrogels with long-term covalent stabilization for cell culture and stem cell transplantation Advanced materials (Deerfield Beach, Fla.), 2011; 23(43): 5098-103.

Carmichael S Thomas Brain Excitability in Stroke: The Yin and Yang of Stroke Progression Archives of neurology, 2011; 23(43): .

Clarkson Andrew N, Overman Justine J, Zhong Sheng, Mueller Rudolf, Lynch Gary, Carmichael S Thomas AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(10): 3766-75.

Savitz Sean I, Chopp Michael, Deans Robert, Carmichael S T, Phinney Donald, Wechsler Larry Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II Stroke; a journal of cerebral circulation, 2011; 42(3): 825-9.

Li Songlin, Overman Justine J, Katsman Diana, Kozlov Serguei V, Donnelly Christopher J, Twiss Jeffery L, Giger Roman J, Coppola Giovanni, Geschwind Daniel H, Carmichael S Thomas An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke Nature neuroscience, 2010; 13(12): 1496-504.

Clarkson Andrew N, Huang Ben S, Macisaac Sarah E, Mody Istvan, Carmichael S Thomas Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke Nature, 2010; 468(7321): 305-9.

Mostany Ricardo, Chowdhury Tara G, Johnston David G, Portonovo Shiva A, Carmichael S Thomas, Portera-Cailliau Carlos Local hemodynamics dictate long-term dendritic plasticity in peri-infarct cortex The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(42): 14116-26.

Carmichael S Thomas Targets for neural repair therapies after stroke Stroke; a journal of cerebral circulation, 2010; 41(10 Suppl): S124-6.

Zhong Jin, Chan Albert, Morad Leeron, Kornblum Harley I, Fan Guoping, Carmichael S Thomas Hydrogel Matrix to Support Stem Cell Survival After Brain Transplantation in Stroke Neurorehabilitation and neural repair, 2010; .

Benowitz Larry I, Carmichael S Thomas Promoting axonal rewiring to improve outcome after stroke Neurobiology of disease, 2010; 37(2): 259-66.

Carmichael S Thomas Translating the frontiers of brain repair to treatments: starting not to break the rules Neurobiology of disease, 2010; 37(2): 237-42.

Clarkson Andrew N, Carmichael S Tomas Cortical excitability and post-stroke recovery Biochemical Society transactions, 2009; 37(Pt 6): 1412-4.

Harris N G, Carmichael S T, Hovda D A, Sutton R L Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited Journal of neuroscience research, 2009; 87(13): 2937-50.

Sozmen Elif G, Kolekar Arunima, Havton Leif A, Carmichael S Thomas A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates Journal of neuroscience methods, 2009; 180(2): 261-72.

Chow David K, Groszer Matthias, Pribadi Mochtar, Machniki Michal, Carmichael S Thomas, Liu Xin, Trachtenberg Joshua T Laminar and compartmental regulation of dendritic growth in mature cortex Nature neuroscience, 2009; 12(2): 116-8.

Gregorian Caroline, Nakashima Jonathan, Le Belle Janel, Ohab John, Kim Rachel, Liu Annie, Smith Kate Barzan, Groszer Matthias, Garcia A Denise, Sofroniew Michael V, Carmichael S Thomas, Kornblum Harley I, Liu Xin, Wu Hong Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(6): 1874-86.

Carmichael S Thomas, Vespa Paul M, Saver Jeffery L, Coppola Giovanni, Geschwind Daniel H, Starkman Sidney, Miller Chad M, Kidwell Chelsea S, Liebeskind David S, Martin Neil A Genomic profiles of damage and protection in human intracerebral hemorrhage Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(11): 1860-75.

Ohab J J, Carmichael S T Poststroke neurogenesis: emerging principles of migration and localization of immature neurons The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2008; 14(4): 369-80.

Miller Chad M, Vespa Paul, Saver Jeffrey L, Kidwell Chelsea S, Carmichael Stanley T, Alger Jeffry, Frazee John, Starkman Sid, Liebeskind David, Nenov Valeriy, Elashoff Robert, Martin Neil Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage Surgical neurology, 2008; 69(5): 441-6; discussion 446.

Carmichael S Thomas Themes and strategies for studying the biology of stroke recovery in the poststroke epoch Stroke; a journal of cerebral circulation, 2008; 39(4): 1380-8.

Popa-Wagner Aurel, Carmichael Stanley Thomas, Kokaia Zaal, Kessler Christof, Walker Lary C The response of the aged brain to stroke: too much, too soon? Current neurovascular research, 2007; 4(3): 216-27.

Ohab John J, Fleming Sheila, Blesch Armin, Carmichael S Thomas A neurovascular niche for neurogenesis after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(50): 13007-16.

Li Songlin, Carmichael S Thomas Growth-associated gene and protein expression in the region of axonal sprouting in the aged brain after stroke Neurobiology of disease, 2006; 23(2): 362-73.

Carmichael S Thomas Cellular and molecular mechanisms of neural repair after stroke: making waves Annals of neurology, 2006; 59(5): 735-42.

Visnyei Koppany, Tatsukawa Keith J, Erickson Rebecca I, Simonian Sharis, Oknaian Nareg, Carmichael S Thomas, Kornblum Harley I Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion Experimental neurology, 2006; 197(2): 465-74.

Tsai Peter T, Ohab John J, Kertesz Nathalie, Groszer Matthias, Matter Cheryl, Gao Jing, Liu Xin, Wu Hong, Carmichael S Thomas A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(4): 1269-74.

Carmichael S Thomas Rodent models of focal stroke: size, mechanism, and purpose NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 2005; 2(3): 396-409.

Carmichael S Thomas, Archibeque Ivonne, Luke Linslee, Nolan Tim, Momiy Janneth, Li Songlin Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex Experimental neurology, 2005; 193(2): 291-311.

Li Songlin, Zheng Jian, Carmichael S Thomas Increased oxidative protein and DNA damage but decreased stress response in the aged brain following experimental stroke Neurobiology of disease, 2005; 18(3): 432-40.

Carmichael S Thomas, Tatsukawa Keith, Katsman Diana, Tsuyuguchi Naohiro, Kornblum Harley I Evolution of diaschisis in a focal stroke model Stroke; a journal of cerebral circulation, 2004; 35(3): 758-63.

Mir Halleh M, Tatsukawa Keith J, Carmichael S Thomas, Chesselet Marie-Francoise, Kornblum Harley I Metabolic correlates of lesion-specific plasticity: an in vivo imaging study Brain research, 2004; 1002(1-2): 28-34.

Carmichael S Thomas Gene expression changes after focal stroke, traumatic brain and spinal cord injuries Current opinion in neurology, 2003; 16(6): 699-704.

Katsman Diana, Zheng Jian, Spinelli Kateri, Carmichael S Thomas Tissue microenvironments within functional cortical subdivisions adjacent to focal stroke Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003; 23(9): 997-1009.

Carmichael S Thomas Plasticity of cortical projections after stroke The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2003; 9(1): 64-75.

Carmichael S Thomas, Chesselet Marie-Françoise Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002; 22(14): 6062-70.

Carmichael S Thomas New laboratory start-up in the 21st century Trends in neurosciences, 2002; 25(6): 287-8. Carmichael S T, Wei L, Rovainen C M, Woolsey T A New patterns of intracortical projections after focal cortical stroke Neurobiology of disease, 2001; 8(5): 910-22.

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